Dr. Donald Hopkins played a leading role in eradicating smallpox, one of humanity's deadliest diseases. After this historic achievement, he devoted his career to fighting Guinea worm disease, a debilitating parasitic infection affecting impoverished communities in Africa. Despite setbacks and challenges, his dogged leadership at the Carter Center has led to dramatic reductions in Guinea worm cases worldwide. Hopkins’s compassion, relentless determination, and innovative methods have made lasting impacts on global public health efforts.